What’s This Research About?

Research on hypermobility is lacking. At the time of this publication there was not a consensus on how to manage the common symptoms of pain and fatigue in this population, hence the impetus for this paper. The authors suss out possible treatment options for hypermobile people suffering from pain and fatigue.

The authors categorized pain into three types.

  1. Nociceptive pain which stems from tissue damage and/or inflammatory response. Current pain science shows that tissue damage will not always cause pain. You can sense pain from tissue damage but not always. As we’ve probably all experienced with never having sensed the root cause of an enormous bruise on our leg.
  2. Neuropathic pain is pathology to either the peripheral or central nerves which can come from compressed or damaged nerves. They will present with entrapped nerves, disc herniation, or axonal neuropathy.
  3. Dysfunctional pain is a central sensitization where the pain is amplified with little stress to the system and can be poorly localized. Fibromyalgia, headache, and irritable bowel syndrome (IBS) are examples of these.

With hypermobility it can be problematic figuring out which type of pain is occurring at any given time making treatment harder to tackle. In general people with JHS can be described as having a “mixed chronic pain syndrome” that has to be treated with a multi-pronged approach.

The second major symptom they cover is fatigue, which is present in 80-90% of those with this condition. They point out that many individuals with chronic fatigue syndrome (CFS) may actually have JHM. They mention that a subtype of CFS could possibly be created in this case.

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